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LYMPHOTOXIN ALPHA1, BETA2 HETEROTRIMER
Descriptors Found:
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DeCS
Descriptor
English
:
Lymphotoxin alpha1, beta2 Heterotrimer
Descriptor
Spanish
:
Heterotrímero de Linfotoxina alfa1 y beta2
Descriptor
Portuguese
:
Heterotrímero de Linfotoxina alfa1 e beta2
Tree Number:
D12.644.276.374.750.505
D12.644.276.972.505
D12.776.467.374.750.505
D12.776.467.972.505
D23.529.374.750.505
D23.529.972.505
Definition
English
:
A heterotrimer complex consisting of one molecule of
LYMPHOTOXIN-ALPHA
and two molecules of the
LYMPHOTOXIN-BETA
. It is anchored to the cell surface via the transmembrane domains of the
lymphotoxin-beta
component and has specificity for the
LYMPHOTOXIN BETA RECEPTOR
. The lymphotoxin alpha1, beta2 heterotrimer plays a
role
in regulating lymphoid
ORGANOGENESIS
and the differentiation of certain subsets of NATURAL KILLER
CELLS.
History Note
English
:
2007
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52294
Unique Identifier:
D053361
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS